Sepio

InfrastructureEndpoint SecurityDetection Response also known as Sepio Systems

Market readinessHow well the company can compete in its security market, scored across eight dimensions against public evidence. Emerging: Market readiness of 24 or below. Below the typical band, where few analyzed companies sit.
DefensibilityHow well the company holds its position if competitors catch up on features, scored across seven dimensions against public evidence. Exposed: Defensibility of 12 or below. The position is exposed as AI lowers the cost of building commodity software.
Founded 2016
Funding $48M
Last updated 2026-07-14

All analysis was generated autonomously, without human review. Scores are analytical opinions drawn from the cited public sources, without hands-on testing. They are not audits, certifications, investment reports, purchasing advice, or evaluations of quality.

Executive Summary

Sepio identifies every device on a network from physical-layer evidence, catching spoofed and rogue hardware that tools relying on network traffic or software agents misidentify. Founded in 2016 with $48 million raised, the company keeps renaming what it sells, from hardware access control to asset risk management to Zero Trust Hardware Access to cyber-physical systems protection, a churn that suggests buyers still lack a dedicated budget line for it. Its most documented sales routes run through partners. Lenovo embeds the technology in ThinkShield, Microsoft's marketplace sells it against committed Azure spend, and CISA awarded it a contract to provide its platform. Named commercial customers stay scarce, though SecurityWeek reported 25-plus bank and telecom deployments in 2019.

Sourced Details

Description Hardware security company whose platform identifies every connected device from physical-layer evidence, flags rogue or spoofed hardware, and enforces device trust policies across IT, OT, and IoT environments. [f1]
Founded 2016 [f2]
HQ Rockville, Maryland, US [f3]
Funding $48M total [f4]
Latest funding Series B extension, $11M (August 2024) [f5]

Products

Product What it does
Sepio Platform Asset risk management platform that discovers connected devices, verifies device identity with AssetDNA physical-layer fingerprinting, scores hardware risk, and enforces trust policies.
Sepio HWDR Expert-managed Hardware Detection and Response service that adds continuous monitoring of hardware assets and hardware-related incidents on top of the Sepio Platform.

Matrix Coverage

Cyber Defense Matrix

IdentifyProtectDetectRespondRecover
Devices Workstations, servers, phones, tablets, storage, network devices, IoT infrastructure, and similar hardware.
Applications Software, interactions, and application flows on the devices.
Networks Connections and traffic flowing among devices and apps, plus communication paths.
Data Content at rest, in transit, or in use across devices, apps, and networks.
Users The people using the devices, apps, networks, and data.

Sepio Platform inventories connected hardware, blocks devices that breach trust policy, and detects rogue or spoofed devices from physical-layer evidence. AssetDNA applies machine learning to a non-AI security problem. The company is mapped to the Cyber Defense Matrix.

Market Readiness

How well the company can compete in its security market, scored across eight dimensions against public evidence.

Emerging 24 /40 Emerging: Market readiness of 24 or below. Below the typical band, where few analyzed companies sit.
Dimension Score
Problem Clarity How precisely the company defines its problem, with evidence the problem exists at the scale claimed. 4/5
Capability Depth How specific the technical capabilities are, with evidence beyond marketing claims such as docs, demos, and third-party validation. 3/5
Market Timing Whether the market is ready for this product, with evidence that buyers are actively seeking solutions. 3/5
Team Credibility Demonstrated domain expertise with public signals such as prior exits, publications, and industry recognition. 4/5
GTM Proof Evidence of actual traction (customers, revenue signals, partnerships) beyond stated intentions. 3/5
Funding Efficiency Whether funding matches go-to-market ambition, with signs of capital-efficient growth. 2/5
Category Clarity Whether the company creates or fits a recognizable category that buyers can quickly place in their stack. 2/5
Incumbent Defensibility How vulnerable the core value proposition is to absorption as a feature by a platform vendor. 3/5

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Business Risks
Problem & Market
Product Capabilities
Competitive Positioning
Go-to-Market & Traction
Team & Credibility
Trust Readiness
Competitors

Strategy Deep Dive

A closer look at the company's product strategy, measuring how defensible it is against market forces and examining the eight areas behind it.

Defensibility

Exposed 12 /21 Exposed: Defensibility of 12 or below. The position is exposed as AI lowers the cost of building commodity software. pivot urgently

Dimension Score
Value Delivery Does the product sell software as the product, or judgment, trust, or accountability with software as the delivery mechanism. 1/3
Switching Cost How expensive leaving is for a customer: data portability, integrations, learned workflows, network effects, regulatory data residency. 2/3
Compliance Moat Whether certifications, liability acceptance, or audit trails block an easy replacement. 1/3
Problem Complexity Whether the product requires ML, optimization, real-time systems, or years of specialized expertise. 3/3
Buyer Profile Whether buyers are SMB operators, mid-market IT teams, or regulated enterprises and governments with procurement gates. 3/3
Layer Whether the product is an end-user application, a platform with application features, or infrastructure other applications depend on. 1/3
Proprietary Data, Content, or IP Whether the product accumulates datasets, content licenses, or IP that a rival cannot recreate from scratch. 1/3

Unlock the Full Analysis

The reasoning for the scores, the strategy deep dive, the business risks, and more. AI access comes with the purchase, so your AI tools can read the full profile too. You keep 12 months of access.

One-time purchase: $20 per profile.

Unlock

Reading several? Unlock the entire catalog.

Strategic Market Segmentation
Product Capabilities & AI Advantages
Sales Engagement & Go-to-Market
Pricing Model
Product Delivery & Operations
Earning Customers' Trust
Platform Strategy & Ecosystem Positioning
Team & Execution Capability

Sources

Company Detail Sources (5)
Id Source Tier Accessed
f1 Sepio homepage official 2026-06-11
f2 Yossi Appleboum leadership bio official 2026-06-11
f3 Sepio MACC eligibility press release press 2026-06-11
f4 Industrial Cyber on the Sepio Series B extension press 2026-06-11
f5 Calcalist on the Sepio Series B extension press 2026-06-11
Profile Analysis Sources (33)
Id Source Tier Accessed
s1 Sepio homepage
“Deliver automated risk mitigation at scale by translating verified device identity into policy enforcement and remediation guidance.”
official 2026-06-12
s2 Sepio about page
“AssetDNA™ fingerprinting (Patented) Identify every device by its unique physical characteristics, no agents required.”
official 2026-06-12
s3 Sepio Platform overview
“Sepio enables this framework through five connected pillars: discovery, verification, validation, risk scoring, and enforcement.”
official 2026-06-12
s4 Sepio HWDR service page
“Sepio HWDR is a continuous, expert-managed Hardware Detection and Response service focused on protecting organizations from hardware-based cyber threats.”
official 2026-06-12
s5 Why Sepio page
“Most security tools can tell you what they think is on the network. Sepio verifies what's physically there, identifies devices for what they truly are (AssetDNA), and then helps you mitigate risk automatically through policy enforcement and remediation guidance.”
official 2026-06-18
s6 ThinkShield Hardware Defense page
“The hardware access control capabilities of the solution block Rogue Devices as soon as they are detected.”
official 2026-06-12
s7 Sepio technology partners page
“Sepio collaborates with leading global cybersecurity technology partners to help organizations integrate comprehensive asset risk management across their infrastructure.”
official 2026-06-18
s8 Sepio leadership page official 2026-06-12
s9 Yossi Appleboum leadership bio
“In 2013, WebSilicon was acquired by Magal (NASDAQ: MAGS).”
official 2026-06-12
s10 Sepio board of directors page official 2026-06-12
s11 Sepio advisory board page official 2026-06-12
s12 Sepio trust center official 2026-06-12
s13 Sepio security certifications page
“we have been awarded SOC 2 Type II, ISO/IEC 27001, ISO/IEC 27017, and ISO/IEC 27018 certifications”
official 2026-06-12
s14 Sepio case studies listing
“Baptist Health keeps patients safe by expanding its Zero Trust approach with Sepio and integrations to their existing tools.”
official 2026-06-12
s15 Sepio government agencies solutions page
“Help comply with regulations, including NDAA Section 889, CISA BOD 23-01, FCC.”
official 2026-06-12
s16 Sepio MSSP solutions page official 2026-06-12
s17 Sepio on its CISA contract and BOD 23-01
“On November 15, 2022, CISA awarded Sepio a contract to implement its Asset Risk Management (ARM) solution.”
official 2026-06-12
s18 Sepio on the ThinkShield partnership
“The integration of ThinkShield Hardware Defense, powered by Sepio, into the newly launched ThinkShield Solutions marks a major milestone. This collaboration significantly advances hardware security for small and medium-sized businesses (SMBs), schools, and other organizations.”
official 2026-06-18
s19 Sepio strategic funding announcement official 2026-06-12
s20 Sepio OT and critical infrastructure page official 2026-06-12
s21 Industrial Cyber on the Series B extension
“The current funding brings the current funds raised to $48 million.”
press 2026-06-12
s22 Sepio Series B announcement
“The previous funding round, which occurred in November 2019, yielded $10 million, bringing the current funds raised to $37 million.”
press 2026-06-12
s23 Calcalist on the Series B extension
“has extended its series B funding round with an additional $11 million investment led by Tau Capital. Sepio announced it had raised $22 million in Series B funding back in October 2022.”
press 2026-06-12
s24 SecurityWeek on the Series A
“has closed a $6.5 million Series A funding round. The funding was led by Hanaco Ventures and Merlin Ventures, with the participation of existing investors Energias de Portugal (EDP), Mindset Ventures and Pico Partners.”
press 2026-06-12
s25 Merlin Ventures portfolio page for Sepio
“Sepio provides actionable visibility to continuously manage risk of all known and shadow assets at any scale.”
other 2026-06-12
s26 Sepio on projected Lenovo partnership revenue
“We are proud to project that this collaboration will generate several million dollars in revenue for Sepio over the next 12 months.”
press 2026-06-12
s27 Sepio MACC eligibility announcement
“ROCKVILLE, Md., Nov. 19, 2025 /PRNewswire/ -- Sepio, the pioneer in hardware-asset risk management, today announced that it is now eligible under the Microsoft Azure Consumption Commitment (MACC)”
press 2026-06-12
s28 Sepio CPS Protection Platform listing on Microsoft marketplace
“CPS, IoT security, asset management, Sepio CPS Protection Platform (MA)”
official 2026-06-12
s29 Sepio Agent installation page official 2026-06-12
s30 Sepio news archive (page 5)
“Erickson, CISO of Baptist Health, sat down with Healthcare Innovation to discuss the implementation of Sepio Systems’ HAC-1 solution.”
official 2026-06-12
s31 CISA Binding Operational Directive 23-01 on federal asset visibility
“all FCEB agencies are required to take the following actions on all federal information systems in scope of this directive”
regulatory 2026-06-30
s32 Israel Companies Registry (data.gov.il): CYBER SEPIO SYSTEMS LTD, company 515429231, incorporated 23/03/2016, status active, last annual report 2025
“"מספר חברה":515429231,"שם חברה":"סייבר ספיו מערכות בע~מ","שם באנגלית":"CYBER SEPIO SYSTEMS LTD","סוג תאגיד":"ישראלית חברה פרטית","סטטוס חברה":"פעילה","תאור חברה":"","מטרת החברה":"לעסוק בכל עיסוק חוקי","תאריך התאגדות":"23/03/2016"”
regulatory 2026-06-30
s33 MITRE CVE record CVE-2023-45866: BlueZ unauthenticated Bluetooth HID keystroke injection
“Bluetooth HID Hosts in BlueZ may permit an unauthenticated Peripheral role HID Device to initiate and establish an encrypted connection, and accept HID keyboard reports, potentially permitting injection of HID messages when no user interaction has occurred”
research 2026-06-30
Deep-Dive Sources (30)
Id Source Tier Accessed
s1 Sepio homepage
“Deliver automated risk mitigation at scale by translating verified device identity into policy enforcement and remediation guidance.”
official 2026-06-11
s2 Sepio about page
“AssetDNA™ fingerprinting (Patented) Identify every device by its unique physical characteristics, no agents required.”
official 2026-06-11
s3 Sepio Platform overview
“The Five Pillars of Zero Trust Hardware Access: discovery, verification, validation, risk scoring, and enforcement. ZTHA addresses that gap by validating the hardware itself.”
official 2026-06-18
s4 Sepio HWDR service page
“Sepio HWDR is a continuous, expert-managed Hardware Detection and Response service focused on protecting organizations from hardware-based cyber threats.”
official 2026-06-11
s5 Why Sepio page
“Most security tools can tell you what they think is on the network. Sepio verifies what's physically there”
official 2026-06-11
s6 ThinkShield Hardware Defense page
“The hardware access control capabilities of the solution block Rogue Devices as soon as they are detected.”
official 2026-06-11
s7 Sepio technology partners page official 2026-06-11
s8 Sepio leadership page official 2026-06-11
s9 Yossi Appleboum leadership bio
“In 2013, WebSilicon was acquired by Magal (NASDAQ: MAGS).”
official 2026-06-11
s10 Sepio board of directors page official 2026-06-11
s11 Sepio advisory board page official 2026-06-11
s12 Sepio trust center
“Sepio's Trust Center Bounty Program reflects our commitment to transparency and proactive cybersecurity. We collaborate with security researchers and responsible disclosure partners to identify and resolve potential vulnerabilities”
official 2026-06-16
s13 Sepio security certifications page
“we have been awarded SOC 2 Type II, ISO/IEC 27001, ISO/IEC 27017, and ISO/IEC 27018 certifications”
official 2026-06-11
s14 Sepio case studies listing
“Baptist Health keeps patients safe by expanding its Zero Trust approach with Sepio and integrations to their existing tools.”
official 2026-06-11
s15 Sepio government agencies solutions page
“Help comply with regulations, including NDAA Section 889, CISA BOD 23-01, FCC.”
official 2026-06-11
s16 Sepio MSSP solutions page official 2026-06-11
s17 Sepio on its CISA contract
“Leverage Sepio's extensive knowledge base, enriched by OSINT (Open Source Intelligence) and proprietary research, to pinpoint vulnerable devices.”
official 2026-06-11
s18 Sepio on the ThinkShield partnership
“The integration of ThinkShield Hardware Defense, powered by Sepio, into the newly launched ThinkShield Solutions marks a major milestone.”
official 2026-06-11
s19 Sepio strategic funding announcement official 2026-06-11
s20 Sepio OT and critical infrastructure page official 2026-06-11
s21 Industrial Cyber on the Series B extension
“It will also go toward allocating resources for Sepio's recently introduced Hardware Detection and Response (HWDR) managed service.”
press 2026-06-11
s22 Sepio Series B announcement
“The representative instrumental in leading USVP's series B funding for Sepio was Dafina Toncheva, a Silicon Valley-based general partner”
press 2026-06-11
s23 Calcalist on the Series B extension
“The company's solution offers customers actionable visibility, policy enforcement and mitigation capabilities and does not require any traffic or activity monitoring.”
press 2026-06-11
s24 SecurityWeek on the Series A
“Cybersecurity startup firm Sepio Systems, with headquarters in Gaithersburg, Maryland and R&D in Tel Aviv, Israel, has closed a $6.5 million Series A funding round.”
press 2026-06-11
s25 Merlin Ventures portfolio page for Sepio
“Sepio provides actionable visibility to continuously manage risk of all known and shadow assets at any scale.”
other 2026-06-11
s26 Sepio on projected Lenovo partnership revenue
“We are proud to project that this collaboration will generate several million dollars in revenue for Sepio over the next 12 months.”
press 2026-06-11
s27 Sepio MACC eligibility announcement
“ROCKVILLE, Md., Nov. 19, 2025 /PRNewswire/ -- Sepio, the pioneer in hardware-asset risk management, today announced that it is now eligible under the Microsoft Azure Consumption Commitment (MACC)”
press 2026-06-11
s28 Sepio CPS Protection Platform listing on Microsoft marketplace
“Sepio CPS Protection Platform (MA) by Sepio Systems. Overview Plans Ratings + reviews Details + support. Get it now”
official 2026-06-18
s29 Sepio Agent installation page official 2026-06-11
s30 Sepio news archive
“CISO Michael Erickson Discusses Implementation of HAC-1 Solution”
official 2026-06-11

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